Sakamakon magani na tafarnuwa

Gringo ya riga ya rubuta labarin mai ban sha'awa game da shi tafarnuwa a Thailand, Ana amfani da tafarnuwa sosai a cikin jita-jita na Asiya. Hakanan kuna ganin tafarnuwa da yawa masu girma da girma a kasuwa a Thailand. A cikin wannan labarin wasu bayanai kan abubuwan da ke inganta lafiyar tafarnuwa. 

Amfani da tafarnuwa na magani ba shi da lokaci. Ba don komai ba ne ake ganin tafarnuwa a matsayin maganin tsufa; Tafarnuwa babu shakka tana magance cututtukan zuciya da jijiyoyin jini, tana inganta kwararar jini zuwa gabobin jiki da kyallen takarda, tana kara karfin garkuwar jiki da kare jiki daga abubuwa masu guba. Bugu da ƙari, tafarnuwa magani ne mai kyau ga cututtuka daban-daban tare da ƙwayoyin cuta, kwayoyin cuta, fungi da parasites.

Tafarnuwa tana da wadata a cikin sinadarai na musamman masu ɗauke da sulfur, babban abin da ke cikin su shine alliin (S-allyl-L-cysteine ​​​​sulfoxide). Alliin (stable) ana canza shi ta hanyar enzyme alliinase zuwa allicin (diallyl thiosulfinate) lokacin da aka yankakken tafarnuwa ko kuma an niƙa. Allicin, wani abu mara ƙarfi, sannan da sauri ya juyo zuwa fiye da ɗari masu aiki metabolites (thiosulfinates). Shirye-shiryen tafarnuwa masu kyau sun ƙunshi alliin, wanda aka canza a cikin hanji da sauran wurare a cikin jiki zuwa metabolites tare da tasirin magani mai karfi (allicine da sauransu).

Tafarnuwa yana rinjayar abubuwan da ke taka muhimmiyar rawa a cikin pathogenesis da ci gaban atherosclerosis. Tafarnuwa tana raguwa gabaɗaya kuma matakan LDL cholesterol da matakan triglyceride, yana ƙaruwa HDL cholesterol mai amfani, yana rage matakan fibrinogen, yana rage hawan jini, yana ƙara fibrinolysis, yana hana haɗuwar platelet kuma yana rage dankon jini. Allicin da S-allylcysteine ​​​​sun kare sel endothelial da LDL-cholesterol daga hadawan abu da iskar shaka kuma suna hana atherosclerosis a wani bangare na kariyar antioxidant. Bugu da ƙari, tafarnuwa kai tsaye yana hana tsarin atherosclerotic ta hanyar hana yaduwar ƙwayoyin tsoka mai santsi a cikin plaques na atherosclerotic da tarin mai a bangon jirgin ruwa.

Tsantsar Tafarnuwa yana rage hawan jini a tsarin hawan jini. Saboda tafarnuwa (a cikin vivo) yana motsa enzyme nitric oxide synthase a cikin endothelium na jijiyoyin jini, samar da vasodilator nitric oxide (NO) yana ƙaruwa. Rage yawan hawan jini kuma saboda hyperpolarization na ƙwayoyin tsoka mai santsi a cikin jini da / ko hana buɗewar tashoshin calcium a cikin ƙwayar tsoka. Hanawar angiotensin-mai canza enzyme (ACE), daidaitawar haɗin prostaglandin ko tasirin tsarin atherosclerosis na iya taka rawa.

Cire tafarnuwa (ciki har da allicin, S-allyl cysteine ​​​​da diallyl disulfide) yana da tasirin antioxidant mai ƙarfi kuma yana ba da kariya daga peroxidation na lipid, yana hana samuwar radicals na superoxide anion radicals kuma yana lalata radicals kyauta. Bugu da ƙari, cin tafarnuwa yana haifar da karuwa a cikin catalase enzymes antioxidant da glutathione peroxidase a cikin jini.
Tafarnuwa tana motsa ayyukan macrophages, lymphocytes da ƙwayoyin kisa na halitta. Ta hanyar hana enzymes lipoxygenase da cyclooxygenase, tafarnuwa yana rage rashin sarrafawa na eicosanoids pro-inflammatory (prostaglandins, leukotrienes da thromboxanes).

Tafarnuwa tana da faffadan ayyukan rigakafin ƙwayoyin cuta kuma tana da tasiri ga ƙwayoyin cuta masu gram-positive da gram-korau, ƙwayoyin cuta, ƙwayoyin cuta da yeasts da fungi ciki har da Candida albicans. Haka kuma ana samun maganin dafin da ƙananan ƙwayoyin cuta ke samarwa da tafarnuwa. Ɗayan MG na allicin yana daidai da ƙarfinsa zuwa kusan 15 IU na penicillin. Tafarnuwa kuma tana da tasiri a kan cututtukan hanji. Alal misali, allicin yana kashe dysenteric amoebae (Entamoeba histolytica) ta hanyar toshe sunadaran cysteine ​​​​da barasa dehydrogenases a cikin amoeba.

Allicin yana hana enzymes na ƙwayoyin cuta, ƙwayoyin cuta da fungi ta hanyar amsawa tare da ƙungiyar thiol (SH ko rukunin sulfhydryl) na enzyme. Dabbobi masu shayarwa suna da ƙarancin sunadarai tare da ƙungiyoyin SH fiye da ƙananan ƙwayoyin cuta. A cikin jikin mutum, glutathione don haka yana kare ƙungiyoyin thiol daga lalacewa. Ƙananan kwayoyin halitta waɗanda ke kula da tafarnuwa, an yi sa'a ba su iya haɓaka juriya ga tafarnuwa saboda zurfin aikin tafarnuwa.
In vitro da in vivo binciken ya nuna cewa tafarnuwa na ƙarfafa tsarin rigakafi, wani ɓangare saboda tasirin antioxidant na tafarnuwa. Allicin da yawa metabolites ciki har da diallyl sulfide (DAS), diallyl disulfide (DADS) da gamma glutamyl methyl selenocysteine ​​​​(GGMSC) ne ke da alhakin wannan.

Di- da trisulfides da allyl mercaptan daga tafarnuwa suma suna lalata karafa masu nauyi kamar su mercury, cadmium da gubar. Ba da mahimmanci ba, abubuwan da ke cikin tafarnuwa suna haifar da enzymes na detoxification na lokaci na II a cikin hanta da sauran gabobin, inganta rushewa da fitar da gubobi da kuma kare jiki daga lokaci mai ƙarfi na detoxification metabolites. Tafarnuwa na kare hanta daga abubuwa masu guba irin su aflatoxin, benzopyrene da acetaminophen. Tasirin tafarnuwa yana raguwa sosai lokacin da sabon tafarnuwa ya yi zafi.

Daga magungunan jama'a an san cewa tafarnuwa yana tallafawa narkewa, yana magance dysbiosis kuma yana inganta ci.

Tafarnuwa na iya rage matakan glucose na jini. Aƙalla abin da binciken dabba ya nuna ke nan. Nazarin ɗan adam ba shi da ƙaranci. Tafarnuwa na iya inganta sakin insulin kuma yana rage rashin kunna insulin.

Alamun sabani

A yi hattara wajen amfani da sinadarin allium sativum kafin a yi tiyata da bayan tiyata da kuma lokacin shan magungunan kashe jini (kamar warfarin, indomethacin da aspirin), kamar yadda tafarnuwa ke rage zubar jini. Allium sativum tsantsa an contraindicated a hali na hypersensitivity zuwa tafarnuwa da kuma yin amfani da protease hana cutar HIV. Tafarnuwa na iya rage girman matakin jini na masu hana protease.

Sakamako na gefen

Wani lokaci yin amfani da ruwan 'ya'yan itace na Allium sativum (musamman a cikin manyan allurai) yana haifar da tashin zuciya, dizziness, gunaguni na ciki ko fushi na mucous membranes a cikin gastrointestinal fili. Rage kashi yawanci yana warware irin waɗannan gunaguni. Rashin lafiyar jiki yana yiwuwa bisa manufa, amma yana da wuyar gaske. Tushen tafarnuwa da kyar ba ta da wani sakamako mai illa.

Mu'amala

Yi hankali lokacin amfani da magungunan rage glucose na jini (sulfonylureas), saboda a hade tare da tafarnuwa, matakin glucose na jini na iya raguwa da yawa. A ka'idar, cire tafarnuwa kuma na iya haɓaka tasirin statins (maganin rage cholesterol) da masu hana ACE (maganin cutar hawan jini). Ba a ba da shawarar yin amfani da manyan allurai na cirewar Allium sativum don dalilai na aminci lokacin amfani da maganin da aka faɗi ba. A ƙarshe, an san cewa cirewar Allium sativum yana ƙarfafa tasirin maganin rigakafi.

Source: Naura foundation