Mushonga wegoriki

Gringo akatonyora nyaya inofadza pamusoro garlic muThailand, garlic inoshandiswa zvakanyanya mumidziyo yeAsia. Iwe zvakare unoona yakawanda yegariki mune ese maumbirwo uye saizi pamusika muThailand. Muchinyorwa chino mamwe mamiriro ezvehutano-ekusimudzira zvinhu zvegariki. 

Kushandiswa kwemishonga yegoriki kwave kuripo nekusingaperi. Hazvisi pasina chikonzero kuti garlic inoonekwa semushonga wekukwegura; Garlic isingarambiki inodzivirira chirwere chemoyo, inovandudza kutenderera kweropa kune nhengo nematishu, inosimbisa immune system uye inodzivirira muviri kubva kune chepfu. Mukuwedzera, garlic ndiyo mushonga wakanakisisa wezvirwere zvakasiyana-siyana nemavhairasi, mabhakitiriya, fungi uye utachiona.

Garlic yakapfuma mune yakasarudzika sarufa-ine makomisheni, icho chikuru chikamu chiri alliin (S-allyl-L-cysteine ​​​​sulfoxide). Iyo (yakagadzika) alliin inoshandurwa kuita allicin (diallylthiosulfinate) neiyo enzyme alliinase apo gariki nyowani inochekwa kana kukuvadzwa. Allicin, chinhu chisina kugadzikana kwazvo, chinobva chashandurwa nekukurumidza kuita anopfuura zana anoshanda metabolites (thiosulfinates). Kugadzirira kwegariki kwakanaka kunonyanya kuve nealliin, iyo inoshandurwa mumatumbo uye kune imwe nzvimbo mumuviri kuita metabolites ine simba rakasimba remishonga (allicin, nezvimwewo).

Garlic inopesvedzera zvinhu zvinotora chikamu chakakosha mupathogenesis uye kufambira mberi kweatherosclerosis. Garlic inoderedza huwandu uye LDL cholesterol mazinga uye triglyceride mazinga, inowedzera inobatsira HDL cholesterol, inoderedza mazinga efibrinogen, inoderedza arterial blood pressure, inowedzera fibrinolysis, inhibits platelet aggregation uye inoderedza viscosity yeropa. Allicin uye S-allylcysteine ​​​​inodzivirira endothelial masero uye LDL cholesterol kubva kune oxidation uye inhibit atherosclerosis chikamu chakavakirwa pakudzivirira antioxidant. Mukuwedzera, garlic inodzivisa zvakananga nzira yeatherosclerotic nekudzivirira kupararira kwemasero akatsetseka emhasuru mu atherosclerotic plaques uye kuunganidza mafuta mumadziro emudziyo.

Garlic inobvisa inodzikisa systemic blood pressure muhypertension. Nokuti garlic (in vivo) inokurudzira enzyme nitric oxide synthase muvascular endothelium, kugadzirwa kwevasodilatory nitric oxide (NO) inowedzera. Kuderedzwa kweropa kunokonzerawo hyperpolarization yemasero anotsvedzerera emhasuru mutsinga dzeropa uye/kana kuvharirwa kwekuvhurwa kwenzira dzecalcium munyama yetsandanyama. Inhibition yeangiotensin-inoshandura enzyme (ACE), modulation ye prostaglandin synthesis kana kufurira atherosclerosis maitiro anogonawo kuita basa.

Garlic inobvisa (inosanganisira allicin, S-allylcysteine ​​​​uye diallyl disulfide) ine yakasimba antioxidant mhedzisiro uye inopa dziviriro kubva kune lipid peroxidation, inodzivirira kuumbwa kwe superoxide anion radicals uye scavenges emahara radicals. Mukuwedzera, kudya kwegariki kunotungamirira kukuwedzera kwe antioxidant enzymes catalase uye glutathione peroxidase muserum.
Garlic inomutsa basa re macrophages, lymphocytes uye masero emuurayi chaiwo. Nekudzivisa ma enzymes lipoxygenase uye cyclooxygenase, garlic inoderedza kusadzora kuumbwa kwepro-inflammatory eicosanoids (prostaglandins, leukotrienes uye thromboxanes).

Garlic ine basa rakakura kwazvo rekurwisa utachiona uye inoshanda kurwisa mabhakitiriya e gram-positive uye gram-negative, mavhairasi, tupukanana uye mbiriso uye howa kusanganisira Candida albicans. Kugadzirwa kwetoxin nema microorganisms aripo zvakare kunopokana negariki. Panyaya yesimba, gigi imwe yeallicin yakaenzana neanenge 15 IU yepenicillin. Garlic inoshandawo kurwisa intestinal parasites. Semuenzaniso, allicin inouraya dysentery-inokonzera amoebae (Entamoeba histolytica) nekuvhara cysteine ​​​​proteinases uye doro dehydrogenases muamoeba.

Allicin inomisa ma enzymes epathogenic bacteria, mavhairasi uye fungi nekuita neboka rethiol (SH kana sulfhydryl boka) reiyo enzyme. Mhuka dzinoyamwisa dzine mapuroteni mashoma nemapoka eSH pane zvipenyu zvakaderera. Mumuviri wemunhu, glutathione saka inodzivirira mapoka etiol kubva mukukuvadzwa. Sezvineiwo, tupukanana tunonzwira gariki hahukwanisi kukudziridza kuramba negariki nekuda kwekuita kwakadzama kwegariki.
In vitro uye in vivo zvidzidzo zvakaratidza kuti gariki inosimbisa immune system, muchidimbu nekuda kwegariki's antioxidant effect. Allicin uye akawanda metabolites anosanganisira diallyl sulfide (DAS), diallyl disulfide (DADS) uye gamma-glutamyl-methylselenocysteine ​​​​(GGMSC) vane mhosva yeizvi.

Di- uye trisulfides uye allyl mercaptan kubva pagariki zvakare chelate inorema simbi senge mercury, cadmium uye lead. Zvisiri zvisingakoshi, zvikamu mugariki zvinokonzeresa chikamu chechipiri che detoxification enzymes muchiropa uye dzimwe nhengo, izvo zvinovandudza kuparara uye kubuda kwehupfu uye inodzivirira muviri kubva kune yakanyanya kuita metabolites kubva muchikamu chekutanga detoxification. Garlic inodzivirira chiropa kubva kune zvine chepfu senge aflatoxin, benzopyrene uye acetaminophen. Mhedzisiro yegoriki inoderedzwa zvakanyanya kana garlic itsva ichipisa.

Kubva kumishonga yevanhu inozivikanwa kuti garlic inotsigira kudya, inopesana nedysbiosis uye inokurudzira chido.

Garlic inogona kuderedza mazinga eglucose muropa. Izvi ndizvo zvinoratidzwa neongororo yemhuka. Zvidzidzo zvevanhu hazvina kujeka. Garlic inogona kuvandudza kuburitswa kwe insulin uye kuve nechokwadi kuti inononoka kusashanda kwe insulin.

Contraindications

Chenjerera paunenge uchishandisa allium sativum yakatorwa pamberi uye pakarepo mushure mekuvhiyiwa uye kana uchishandisa anticoagulant mishonga (yakadai sewarfarin, indomethacin uye aspirin), sezvo gariki inononoka kugwamba kweropa. Allium sativum extract inopesana kana iine hypersensitivity kune garlic uye kushandiswa kweprotease inhibitors kurwisana nehutachiona hweHIV. Garlic inogona kuderedza zvakanyanya kuwanda kweropa reprotease inhibitors.

Zvikanganiso

Dzimwe nguva kushandiswa kweAllium sativum zvinyorwa (kunyanya muhuwandu hwepamusoro) kunotungamirira kusvotwa, dzungu, kunyunyuta kwemudumbu kana kutsamwiswa kwemucous membranes mumugwagwa wegumbo. Kuderedza dose kunowanzogadzirisa zvichemo zvakadaro. An allergic reaction in musimboti zvinogoneka, asi hazviwanzo. Garlic yakaviriswa haina zvishoma kana isina mhedzisiro.

Kudyidzana

Chenjerera kana uchishandisa mishonga inoderedza shuga yeropa (sulfonylureas), nekuti pamwe chete negariki iyo glucose yeropa inogona kudonha zvakanyanya. Garlic inobvisa inogonawo kusimbisa mhedzisiro ye statins (cholesterol-inoderedza mishonga) uye ACE inhibitors (mishonga inopesana neBP). Kushandiswa kwemhando yepamusoro yeAllium sativum yakatorwa hakukurudzirwe nekuda kwezvikonzero zvekuchengetedza kana uchishandisa mushonga wambotaurwa. Chekupedzisira, zvinozivikanwa kuti Allium sativum inobvisa inogonesa mhedzisiro yemishonga inorwisa mabhakitiriya.

Kunobva: Naura hwaro